GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
THCA | cis | rs4911414 | 1 | rs4911410 | chr20:32710974 | RALY | chr20:32581732-32672675:+ | 0.14 | 4.34 | 1.77E-5 | Tanning;Skin sensitivity to sun;Red vs. non-red hair color;Freckles;Burning and freckling |
THCA | cis | rs4911414 | 1 | rs4911412 | chr20:32716435 | RALY | chr20:32581732-32672675:+ | 0.14 | 4.26 | 2.44E-5 | Tanning;Skin sensitivity to sun;Red vs. non-red hair color;Freckles;Burning and freckling |
THCA | cis | rs4911414 | 1 | rs4911414 | chr20:32729444 | RALY | chr20:32581732-32672675:+ | 0.14 | 4.24 | 2.69E-5 | Tanning;Skin sensitivity to sun;Red vs. non-red hair color;Freckles;Burning and freckling |
THCA | cis | rs6088813 | 1 | rs4911491 | chr20:33947285 | CEP250 | chr20:34042996-34099802:+ | -0.15 | -3.37 | 0.000804 | Height |
THCA | cis | rs6088813 | 1 | rs4911491 | chr20:33947285 | CPNE1 | chr20:34213968-34262539:- | 0.3 | 5.95 | 5.17E-9 | Height |
THCA | cis | rs6088813 | 1 | rs4911491 | chr20:33947285 | GDF5 | chr20:33897002-34042568:- | -0.18 | -3.81 | 0.000154 | Height |
THCA | cis | rs6088813 | 1 | rs4911491 | chr20:33947285 | UQCC | chr20:33890383-33999833:- | 0.32 | 10.23 | 2.48E-22 | Height |
THCA | cis | rs6088813 | 1 | rs4911492 | chr20:33951799 | CEP250 | chr20:34042996-34099802:+ | -0.15 | -3.38 | 0.000792 | Height |
THCA | cis | rs6088813 | 1 | rs4911492 | chr20:33951799 | CPNE1 | chr20:34213968-34262539:- | 0.3 | 5.92 | 6.1E-9 | Height |
THCA | cis | rs6088813 | 1 | rs4911492 | chr20:33951799 | GDF5 | chr20:33897002-34042568:- | -0.18 | -3.82 | 0.000152 | Height |
THCA | cis | rs6088813 | 1 | rs4911492 | chr20:33951799 | UQCC | chr20:33890383-33999833:- | 0.32 | 10.21 | 2.76E-22 | Height |
THCA | cis | rs6088813 | 1 | rs4911494 | chr20:33971914 | CEP250 | chr20:34042996-34099802:+ | -0.15 | -3.37 | 0.000804 | Height |
THCA | cis | rs6088813 | 1 | rs4911494 | chr20:33971914 | CPNE1 | chr20:34213968-34262539:- | 0.3 | 5.95 | 5.17E-9 | Height |
THCA | cis | rs6088813 | 1 | rs4911494 | chr20:33971914 | GDF5 | chr20:33897002-34042568:- | -0.18 | -3.81 | 0.000154 | Height |
THCA | cis | rs6088813 | 1 | rs4911494 | chr20:33971914 | UQCC | chr20:33890383-33999833:- | 0.32 | 10.23 | 2.48E-22 | Height |